Key Largo is connected to the mainland in Miami-Dade County by two routes. The first route is The Overseas Highway, which is U.S. Highway 1 that enters Key Largo at Jewfish Creek near the middle of the island and turns southwest. The second route is Card Sound Road, which connects to the northern part of Key Largo at Card Sound Bridge and runs southeastward to connect with County Road 905, which runs southwest and joins U.S. 1 at about mile marker 106. These routes originate at Florida City on the mainland.